Valkude kvaternaarstruktuur Moodustub individuaalsete polüpeptiidahelate subühikute omavahelisel assotsiatsioonil Subühikute assotsiatsioon enamast mittekovalentne Monomeerne, oligomeerne, multimeerne valk Dimeerne, trimeerne, tertameerne jne. Kõige laiemalt on levinud dimeerid Identsed või sarnased subühikud homo: Homodimeer, homotrimeer jne. Erinevad subühikud hetero: Heterodimeer, heterotrimeer jne. Ribonuclease A (C575H901N171O193S12)
A protein complex forms that contains additional cleavage factors and the enzymePolyadenylate Polymerase (PAP). This complex cleaves the RNA between the polyadenylation sequence and the GU-rich sequence at the cleavage site marked by the (5'- CA-3') sequences. Poly(A) polymerase then adds about 200 adenine units to the new 3' end of the RNA molecule using ATP as a precursor. As the poly(A) tail is synthesised, it binds multiple copies of poly(A) binding protein, which protects the 3'end from ribonuclease digestion.[4] [edit]Splicing Main article: RNA splicing RNA splicing is the process by which introns, regions of RNA that do not code for protein, are removed from the pre-mRNA and the remaining exons connected to re-form a single continuous molecule. Although most RNA splicing occurs after the complete synthesis and end-capping of the pre-mRNA, transcripts with many exons can be spliced co-transcriptionally.[5] The
A protein complex forms that contains additional cleavage factors and the enzymePolyadenylate Polymerase (PAP). This complex cleaves the RNA between the polyadenylation sequence and the GU-rich sequence at the cleavage site marked by the (5'- CA-3') sequences. Poly(A) polymerase then adds about 200 adenine units to the new 3' end of the RNA molecule using ATP as a precursor. As the poly(A) tail is synthesised, it binds multiple copies of poly(A) binding protein, which protects the 3'end from ribonuclease digestion.[4] [edit]Splicing Main article: RNA splicing RNA splicing is the process by which introns, regions of RNA that do not code for protein, are removed from the pre-mRNA and the remaining exons connected to re-form a single continuous molecule. Although most RNA splicing occurs after the complete synthesis and end-capping of the pre-mRNA, transcripts with many exons can be spliced co-transcriptionally.[5] The
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