dilution, and they are relatively irregularly shaped. All of the cats were Persian and resembled blue smoke Persians. The pink-eyed dilute cat hair had very small yellowish-brown melanin granules and very few larger granules. Under the microscope, some lighter banding could be seen on the hairs, but the tip was coloured. The base of the hair was paler than the tip (agouti banding). - Prieur DJ, Collier LL. Morphologic basis of inherited coat-color dilutions of cats. J Hered. 1981 May-Jun;72(3):178-82. BLUE DILUTION The normal dilution seen in cats is "blue dilution" that changes black to grey (blue), chocolate to lilac, and cinnamon to fawn. Blue dilution affects the skin and coat colour by altering the pigmentation granules, but leaves the eyes pigmented. How Blue Dilution Affects Different Colours Prieur DJ, Collier LL. Maltese dilution of domestic cats. A generalized cutaneous albinism lacking ocular involvement
determination of absolute detection and Food and Feed of the Joint Research Centre quantification limits of the method, while a (JRC) of the European Commission has correct determination of the practical quanti- defined minimum performance requirements fication limits requires a thorough statistical for analytical methods of GMO testing examination of the sampling procedure when ( http://gmo-crl.jrc.ec.europa.eu/doc/Min_ preparing the serial dilutions, based on bino- Perf_Requir_Analyt_methods_131008.pdf). mial distributions and Monte-Carlo simula- tions (Hernandez et al. 2003a). Finally, Use of Certified Reference Materials careful analysis and interpretation of data from the real-time PCR method have to be The use of certified reference materials performed properly, with the use of the (CRM) is needed in RTi-PCR systems for
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