anterioorosa ümber. Neuraalvall areneb otse ventraalseks vaheajuksiks. See keskjoone neuraalvall, mis paikneb neelu kohal, moodustab Rathke tasku ehk sopi, mis sopistub ventraalselt vaheajju. Koos moodustavad nad ajuripatsi, eesmine osa pärineb Rathke sopist, tagumine aga ventraalsest vaheajust. Kuus Rathke sopis olevat peamist rakutüüpi on: · Corticotrope'd, mis toodavad proopiomelanocotriini (POMC) ja seovad selle adrenocorticotropic hormooniga( ACTH), mida on tarvis glucoicorticoidi sünteesiks neerupealsetes. · Melanotrope'd, mis toodavad POMCd kuid seovad selle melanocyte'e stimuleeriva hormone-'ga (pigmentide moodustamiseks, toitumise reguleerimiseks). · Somatotrope'd, mis toodavad kasvuhormooni (rakkude paljunemiseks). · Lactotrope'd mis toodavad prolaktiini (piima tootmiseks, emaka kokkutõmmete reguleerimiseks).
, 2002,). Psychological and other forms of stress influence the sympathetic nervous system, hypothalamuspituitary adrenal (HPA) - axis, and immune system; the interaction between these systems is complex (Raison et al., 2003, Pariante & Miller, 2001; Adler, Felten & Cohen, 2001). Activation of the HPA axis by physical or psychological stress begins with corticotrophin-releasing hormone (CRH) secretion from the Hypothalamus, CRH then signals the Anterior Pituitary gland to secrete Adrenocorticotropic hormone (ACTH), ACTH then acts on the Adrenal gland which then produces glucocorticoids such as corticosterone and cortisol (Figure 3) which have important metabolic and immunological effects (Arzt, 2001; Hoffman-Goetz & Pederson, 1994; Fitzgerald, 1998). Emotion regulation in relation.. 1 Figure 3. The Hypothalamic-Pituitary-Adrenocortical Axis (HPA) Cortisol has been widely used in psychology to measure stress
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