"vasculature" - 1 õppematerjal

Immunoloogia eksami kordamisküsimused

of phagocytosis, complement activation, antibody-dependent cellular cytotoxicity (ADCC), genetically modified T cells being targeted to the tumor by single-chain variable fragment (scFv), T cells being activated by antibody-mediated cross-presentation of antigen to dendritic cells, and inhibition of T cell inhibitory receptors, such as cytotoxic T lymphocyte- associated antigen 4 (CTLA4). c) Vascular and stromal cell ablation can be induced by vasculature receptor antagonism or ligand trapping (not shown), stromal cell inhibition, delivery of a toxin to stromal cells, and delivery of a toxin to the vasculature. Immunoteraapia 1. Madalate kostimulatoorsete signaalide võimendamine Antigeeni presenteerivate rakkude aktiivsuse suurendamine ­ viies kasvajarakkudesse GM-CSF-i geeni- kasvaja tootes seda aktiveerib DC ­ Kasvajarakkudesse B7 viimine ja sellega kostimulatoorse signaali võimendamine