Mittesteroidsete põletikuvastaste ravimite farmakoloogia
CHEMISTRY
Sulindac is related closely to indomethacin; its structure is:
injection.
milk, or antacids to lessen abdominal discomfort. Peak plasma concentration
ity are reduced when the drug is taken with food.
Heteroarüüläädikhapped
t commonly
COMMONused tNSAID
og of diclofenac.
ADVERSE in Europe.
EFFECTS The selective inhibitor of COX-2
Side effects occur in 2540% of patients who take tolmetin, and 510% dis
drug. Gastrointestinal side effects are the most common (15%) and gastric u
observed. CNS side effects similar to those seen with indomethacin and aspirin
less common and less severe.
Ketorolac
Ketorolac is a potent analgesic but only a moderately effective anti-inflamma
of the few NSAIDs approved for parenteral administration.
AL PROPERTIES
sic, antipyretic, and anti-inflammatory activities. Diclofenac appears to
annaabi.ee 
