"tnsaid" - 1 õppematerjal

Mittesteroidsete põletikuvastaste ravimite farmakoloogia

Sulfoonaniliidid - nimesuliid Para-aminofenoolid - paratsetamool Salitsülaadid Propioonhapete derivaadid Indoolid 448 SECTION IV Autacoids: Drug Therapy of Inflammation Sulindac CHEMISTRY Sulindac is related closely to indomethacin; its structure is: injection. milk, or antacids to lessen abdominal discomfort. Peak plasma concentration ity are reduced when the drug is taken with food. Heteroarüüläädikhapped t commonly COMMONused tNSAID og of diclofenac. ADVERSE in Europe. EFFECTS The selective inhibitor of COX-2 Side effects occur in 25­40% of patients who take tolmetin, and 5­10% dis drug. Gastrointestinal side effects are the most common (15%) and gastric u observed. CNS side effects similar to those seen with indomethacin and aspirin less common and less severe. Ketorolac