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"shigellosis" - 1 õppematerjal

Liha töötlemine
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Liha töötlemine

The cell wall of Shigella, when lysed, will impairs the sodium pump of mammalian release endotoxins. In addition, S. dysente- cells, thus causing severe diarrhea, dehydra- riae produces an exotoxin that is a highly tion, acidosis, shock, and even death. The toxic neurotoxin. This toxin can be neutral- mortality rate may be as high as 25% to 50%. ized by a specific antibody. The mortality The most effective therapy is replacement of rate of shigellosis is higher than that of water and electrolytes to correct severe dehy- salmonellosis. Prevention of shigellosis can dration and salt depletion. be achieved by sanitation, good hygiene, Vibrio cholerae remains a dreaded com- water treatment, prevention of contamina- municable disease in many parts of the tion, detection of carriers, and isolation of world, and much education and public health patients from the general public

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