more sensitive than conventional laboratory animals. · General toxicity after repeated administration The main endpoint of aniline after repeated dosing is toxicity to the haematopoietic system with erythrotoxicity, methaemoglobinaemia, haemolytic anaemia and formation of Heinz bodies, with corresponding changes of the spleen, the bone marrow, the kidneys and the liver. The damaged red blood cells are scavenged predominantly in the red pulp of the spleen, followed by increased haemosiderin accumulation. Experience from humans after repeated oral intake gives indications of haematotoxicity at dosages from 0.4 mg/kg bw/day. b) Reproduction toxity · Developmental toxicity The critical exposure level for potential developmental toxicity has been determined to be 150 mg/person/day or 15 mg/m3. · Reproduction toxicity
The new recruits are younger than ever before and have no training. Wounded men are sent back to fight before they are healed; even crippling physical defects do not save them from combat duty. Leer bleeds to death from a thigh wound. The summer of 1918 is horrific. Though they are obviously losing, the Germans keep fighting. Rumors of a possible end to the war make the soldiers more reluctant to return to the front lines. Kat is wounded while returning with food that he has scavenged. Paul cannot leave him to find a stretcher because Kat is bleeding too much. Paul painstakingly carries him to the dressing station while shells crash around him. Kat is the only friend Paul has left in the army. When he reaches the station, still carrying Kat, he discovers that Kat has been hit in the head by a fragment from an exploding shell. Paul's dearest friend is dead. Chapter Twelve Summary In the autumn of 1918, after the bloodiest summer in Paul's wartime experience, Paul is the
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