The 4-Hour Body - An Uncommon Guide to Rapid Fat-Loss, Incredible Sex, and Becoming Superhuman - Timothy Ferriss
myosin (thick laments)--that slide over each other to cause muscles to
contract, a literal shortening of the muscle. Actin laments, which are necessary to this process,
are stabilized by actin-binding proteins. One actin-binding protein called alpha-actinin 3
(ACTN3) is expressed only in fast-twitch muscle ber, the crown jewel of shot-putters and
bodybuilders worldwide.
It turns out that both of my chromosomes (one from Mammy and one from Pappy Ferriss)
contain the R577X variant of the ACTN3 gene, a mutation that results in a complete de ciency
of our most desired ACTN3. This variant, amusingly called a "nonsense allele," is found in more
than a billion humans worldwide.
Sad Christmas.
The cover letter from Gist Sports began with the following headline, which, in good humor,
lacks an exclamation point:
Congratulations Tim Ferriss. Your Genetic Advantage: Endurance Sports.
annaabi.ee 
