Capillary electrophoresis i.k.
migration times is achieved.
Detection
Because of the small size of the capillary and therefore small amount of the sample to the
detection in HECE imposed special requirements. Although in CE is needed only nanoliter
of volume samples, it is definitely not a method of analysis in trace amounts, as it requires a
relatively concentrated solution of the sample or method preconcentration. Most methods for
detecting very similar to the methods of liquid chromatography. As in HPLC, the most
commonly used UV detection. Table. 3 lists the various detection methods with relevant
detection limits, as well as their advantages and disadvantages.
Table 3: Detection methods in CE
Method Detection limits Advantages/disadvantages