Capillary electrophoresis i.k.
electrophoretic separation and analysis of protein mixtures by free or moving boundaries. The
main disadvantage of this method was the heat liberation during the electriс current passing
through the liquid because that prevented for clear division of factions and led to a blurring of
the boundaries between the individual zones. In 1940, D. Philpot suggested to use columns
with a density gradient of buffer solutions, and in the 50s years the method has been refined
and was developed the device for electrophoresis in density gradient.
However, the method was deficient, because after switching off the electric current, formed
during electrophoresis zones have "blurred". Subsequent achievements in electrophoresis