Liha töötlemine
Nitric Oxide and S-Nitrosylation
much like phosphorylation (Jaffrey et al.
Nitric oxide (NO) is often used as a general 2001). Some proteins, such as the ryanodine
term that includes NO and reactive nitrogen receptor and the cysteine protease caspase-
species (RNS), like S-nitrosothyols, per- 3, have been shown to be endogenously
oxynitrate, and metal NO complexes. In nitrosylated, further supporting the sugges-
living tissue, NO is involved in arteriole dila- tion that formation of nitrosothiols may be
tion that increases blood flow to muscles, an important regulatory step (Hess et al.
resulting in increased delivery of nutrients 2001; Hess et al. 2005). μ-Calpain is also
and oxygen to the muscle (Kobzik et al. a cysteine protease that could be influenced
1994; Stamler et al. 2001). NO species are by S-nitrosylation
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