Liha töötlemine
fragi (Fang and Lin 1994). In order to sensi- Government approval is needed in order
tize Gram-negatives to nisin, chelators or to take advantage of the variety of bacterio-
bacterial membrane disruptors, such as cins present in nature. To date, nisin is the
EDTA, Tween-80, or high hydrostatic pres- only approved bacteriocin. Nisin can be used
sure (HHP), might be required (Natrajan and to control Gram-positive bacteria, such as the
Sheldon 2000b; Galvez et al. 2007). pathogen L. monocytogenes and the spoiler
Application of nisin in meat products is B. thermosphacta. Although methods of sen-
somewhat challenging due to its binding sitizing Gram-negatives are well known, the
ability to meat components, low solubility major drawback of nisin is its loss of activity