"methaemoglobin" - 1 õppematerjal

Aniliini riskianalüüs (eng)

Solubility in ethanol: perfectly Viscosity: 3.71 cP (3.71 mPa·s at 25 °C) pH: >7 log Pow: 0.90/0.98 Koc: 25,5 3. Kinetics and metabolism The substance can be absorbed into the body by inhalation, through the skin and by ingestion, also as a vapour. The mean lethal dose of aniline may be between 15 and 30 grams. In case of short-term exposure the substance is irritating to the eyes and the skin. The substance may cause effects on the blood, resulting in the formation of methaemoglobin. Exposure at high levels may result in death. Repeated or prolonged contact may cause skin sensitization. The substance may have effects on the blood, resulting in formation of methaemoglobin. Tends to accumulate in the body, especially in bladder. Often leads to bladder cancer. Aniline was tested on animals, but in mice was observed no increase in tumour incidence, in rats, it produced fibrosarcomas, sarcomas and haemangiosarcomas of the spleen and peritoneal cavity. 4. Behavior in the wild