Molekulaarbioloogia praksi kontrolltöö vastused
promoters, can confer transcriptional activation via all three RARs.
· Nimeta RA-reguleeritud märklaud geene.
Some of these genes are the homeotic genes that specify the position of the cell along the
anterior-posterior axis and therefore will cause the cell to display different characteristics.
(2) They repress the activity of the AP-1 transcription factor. This transcription factor is
important in activating those genes responsible for cell division and for the production of
metalloproteinases that often permit cell migration.
Nimeliselt...HOX 1-4
· Missugune on lisatava retinoolhappe töökontsentratsioon? Miks just selline?
Millised RA konversioonid rakus toimuvad ja missugused on erinevate
derivaatide afiinsused erinevatele retseptoritele?
· Kirjelda RA retseptorite sidumissaite.
RAR has 3 domains: N-terminal, DNA-binding and C-terminal RA binding domain.
DNA siduv sait on vist tsink-sõrm tüüpi...
· Loetle teisi tuumahormooniretseptorperekondi.
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