Liha töötlemine
ture of the myofibrillar sarcomere and integ- nebulin is embedded into the Z-line. Nebulin
rity of muscle. This weakening, in conjunction is highly nonextensible and has been referred
with other changes in postmortem muscle, to as a molecular ruler that during develop-
could lead to enhanced tenderness. The deg- ment may serve to define the length of the
radation of titin has been observed in several thin filaments (Kruger et al. 1991). Nebulin,
studies (Lusby et al. 1983; Zeece et al. 1986; via its intimate association with the thin fila-
Astier et al. 1993; Huff-Lonergan et al. 1995; ment (Lukoyanova et al. 2002), has been
Melody et al. 2004; Rowe et al. 2004a, b). hypothesized to constitute part of a compos-
When titin is degraded, a major degradation ite nebulin/thin filament (Pfuhl et al. 1994;
product, termed T2, is observed that migrates Robson et al. 1995) and may aid in anchoring
annaabi.ee 
