Aniliini riskianalüüs (eng)
to be 150 mg/person/day or 15 mg/m3.
· Reproduction toxicity
No effects in any of the organs of the reproductive system of either males or females
(for mice). No information is available on the reproductive effects of aniline in
humans.
· Teratogenicity
Toxic starting from 21 mg aniline/kg bw/day.
c) Carcinogenicity
Aniline is currently classified as carcinogenic, category 3 and labelled with R40
"limitedevidence of a carcinogenic effect". Animal studies have shown an increase in
tumors of the spleen in rats exposed to aniline hydrochloride. EPA calculated an oral
cancer slope factor of 5.7 x 10-3 (mg/kg/d) -1 and an oral unit risk estimate of 1.6 × 10- 7
(µg/L)-1.
d) Genotoxicity and mutagenicity
Aniline did not induce unscheduled DNA repair in primary human or rat hepatocytes. In
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