Synthesis of Ibuprofen
F-test has to be made to make sure if the means have equivalent precisions.
Depending of the outcome of F-test following t-test will be made
Optimization
Another synthesis procedure e.g. Boots' synthesis
procedure.
Increase the speed of forming Grignard formation,
which minimizes coupling. For this use
mechanically activated magnesium.
Decrease the degree of coupling by lowering
temperature.
To shorten the synthesis, it is possible to go from
starting ketone directly to the chloride without
isolating alcohol.
annaabi.ee 
