The 4-Hour Body - An Uncommon Guide to Rapid Fat-Loss, Incredible Sex, and Becoming Superhuman - Timothy Ferriss
First and foremost, I wanted to increase muscular absorption of the calories
(and supplements) I consumed, and ALA turned out to be the perfect force multiplier. More
calories absorbed into muscle meant fewer calories deposited as fat and faster strength gains.
ALA accomplishes this, in part, by recruiting GLUT-4 glucose transporters to the muscular cell
membrane. This both mimics insulin and increases insulin sensitivity, and ALA is therefore
being explored as an "insulino-mimetic" that can be used to treat type 2 diabetes and metabolic
syndrome.
Not only does ALA increase glucose and nutrient absorption, but it also demonstrates
triglyceride inhibition and--through extrapolation--fat storage. Here is an abstract from a 2009
article from the Archives of Biochemistry and Biophysics that drives the point home:
Livers from LA [lipoic acid]treated rats exhibited elevated glycogen content, suggesting