Mittesteroidsete põletikuvastaste ravimite farmakoloogia
ADVERSE in Europe.
EFFECTS The selective inhibitor of COX-2
Side effects occur in 2540% of patients who take tolmetin, and 510% dis
drug. Gastrointestinal side effects are the most common (15%) and gastric u
observed. CNS side effects similar to those seen with indomethacin and aspirin
less common and less severe.
Ketorolac
Ketorolac is a potent analgesic but only a moderately effective anti-inflamma
of the few NSAIDs approved for parenteral administration.
AL PROPERTIES
sic, antipyretic, and anti-inflammatory activities. Diclofenac appears to
oncentrations of free AA in leukocytes, perhaps by altering its release or
PHARMACOLOGICAL PROPERTIES
Para-aminofenoolid
Selektiivsed COX-2 inhibiitorid e koksiibid
Diarüülasendusega furanoonid rofekoksiib (ei turustata)
Diarüülasendusega pürasoolid - tselekoksiib
Bipüridiini derivaadid - etorikoksiib