Sidumissait - regioon (valgus, DNA-s jne), mis on spetsiifiliseks seostumiseks teistele molekulidele, ioonidele. It is a region on a protein, DNA, or RNA to which specific other molecules and ions -- in this context collectively called ligands, or more specifically, protein ligands -- form a chemical bond. 3. TATA-box is a DNA sequence (Cis-regulatory element) found in the promoter region of most genes in eukaryotes. It is the binding site of either transcription factors or histones and is involved in the process of transcription by RNA polymerase. It has the core DNA sequence 5'- TATAAA-3' or a variant, which is usually followed by three or more adenine bases and has been highly conserved through evolution. The TATA box is usually located 25 base pairs upstream to the transcription site. 4. Nimeta peamised DNAd siduvad domäänid, mis on iseloomulikud transkript-sioonifaktoritele (vähemalt 3) a
TBP is also a necessary component of RNA polymerase I and RNA polymerase III, and is, it is thought, the only common subunit required by all three of the RNA polymerases. · HAT histoonide atsetüültranseferaas. Histone acetyltransferases (HATs) are enzymes that acetylate conserved lysine amino acids on histone proteins by transferring an acetyl group from acetyl CoA to form -N-acetyllysine. DNA is wrapped around histones, and by transferring an acetyl group to the histones, genes can be turned on and off. Histone acetylation increases gene expression. In general, histone acetylation is linked to transcriptional activation and associated with euchromatin. Jaguneb A tüüpi (nukleosoomis) ja B tüüpi (tsütoplasmasa) HAT'deks. · Transkriptsioon on matriitssüntees, mille käigus sünteesitakse DNA molekuli ühe ahela
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