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If spoilage bacterial of 100 to 900 MPa. HHP processing is numbers are low on a product due to the considered nonthermal, since temperatures effectiveness of other control measures, then increase only 3°C for every 100 MPa applied phage treatment may not be valuable. (Aymerich et al. 2008). Equipment for HHP However, in the case of refrigerated meat is commercially available, including manu- spoilage, where generally large population facturers Avure Technologies (United States) numbers are present, phage technology may and Nicolas Correa Hyperbaric (Spain). HHP have merit. kills bacterial cells through a combination of The nature of the environment can play a actions, with the bacterial membrane the significant role in phage attack, with viscous primary site of damage. Gram-negative

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