Liha töötlemine
walls of the large intestines and ileum. endotoxins in the intestines and causes severe
Invasion of the blood is rare. Bloody stool irritation to the mucous membranes, with
will occur, owing to superficial ulceration. resultant outflow of fluid and salts, and
The cell wall of Shigella, when lysed, will impairs the sodium pump of mammalian
release endotoxins. In addition, S. dysente- cells, thus causing severe diarrhea, dehydra-
riae produces an exotoxin that is a highly tion, acidosis, shock, and even death. The
toxic neurotoxin. This toxin can be neutral- mortality rate may be as high as 25% to 50%.
ized by a specific antibody. The mortality The most effective therapy is replacement of
rate of shigellosis is higher than that of water and electrolytes to correct severe dehy-
salmonellosis. Prevention of shigellosis can dration and salt depletion.
annaabi.ee 
