Histone acetyltransferases (HATs) are enzymes that acetylate conserved lysine amino acids on histone proteins by transferring an acetyl group from acetyl CoA to form -N-acetyllysine. DNA is wrapped around histones, and by transferring an acetyl group to the histones, genes can be turned on and off. Histone acetylation increases gene expression. In general, histone acetylation is linked to transcriptional activation and associated with euchromatin. Jaguneb A tüüpi (nukleosoomis) ja B tüüpi (tsütoplasmasa) HAT'deks. · Transkriptsioon on matriitssüntees, mille käigus sünteesitakse DNA molekuli ühe ahela nukleotiidse järjestusega komplementaarne RNA molekul. Protsess toimub rakutuumas interfaasi ajal. Seda viib läbi ensüüm RNA-polümeraas, mis peab transkriptsiooni alustamiseks seostuma vastava geeni algusosaga. DNA nukleotiidset järjestust, millega
M. and Karpen,G.H. TITLE Heterochromatic sequences in a Drosophila whole-genome shotgun assembly JOURNAL Genome Biol. 3 (12), RESEARCH0085 (2002) PUBMED http://www.ncbi.nlm.nih.gov/pubmed/12537574?dopt=Abstract REFERENCE 3 (bases 1 to 2693) AUTHORS Kaminker,J.S., Bergman,C.M., Kronmiller,B., Carlson,J., Svirskas,R., Patel,S., Frise,E., Wheeler,D.A., Lewis,S.E., Rubin,G.M., Ashburner,M. and Celniker,S.E. TITLE The transposable elements of the Drosophila melanogaster euchromatin: a genomics perspective JOURNAL Genome Biol. 3 (12), RESEARCH0084 (2002) PUBMED http://www.ncbi.nlm.nih.gov/pubmed/12537573?dopt=Abstract REFERENCE 4 (bases 1 to 2693) AUTHORS Misra,S., Crosby,M.A., Mungall,C.J., Matthews,B.B., Campbell,K.S., Hradecky,P., Huang,Y., Kaminker,J.S., Millburn,G.H., Prochnik,S.E., Smith,C.D., Tupy,J.L., Whitfied,E.J., Bayraktaroglu,L., Berman,B.P., Bettencourt,B.R., Celniker,S.E., de Grey,A.D., Drysdale,R.A., Harris,N.L., Richter,J
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