Exercise Physiology - lecture 4 Blood, gas exchange, transport
bonding strength (affinity) between Hb and O2.
O2-hb disassociation curve
Oxygen-haemoglobin Dissociation curve
High drop in PO2
associated with only slight
changes in O2 saturation.
As PO2 of blood increases
saturation increases.
As PO2 of blood decreases
affinity between O2 and Hb
decreases and O2
disassociates from Hb.
Unloading of oxygen to
tissue
Haemoglobin Saturation & pH
Low blood pH
(high PCO2)
Normal
blood pH
High blood pH
(low PCO2)
Everest
Oxygen Saturation & pH
When the blood becomes more acidic (increased CO2 and
H+) the curve shifts to the right.
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