lesions, since both findings strongly affect prognosis.[5] In general, less expensive, less invasive, and less risky tests are offered first, although owners should be made aware that more expensive, more invasive tests may follow if diagnosis is not achieved. For example, fine needle aspiration and cytologic evaluation are often recommended prior to surgical removal and biopsy of a mass. For many tumor types, such as lymphoma and mast cell tumors, diagnosis is usually easily achieved with cytology, and knowledge of the diagnosis prior to surgery augments treatment planning. For spindle cell tumors, such as fibrosarcoma or hemangiopericytoma, diagnostic cytologic samples are not always obtained, and a biopsy may need to be performed to achieve a definitive diagnosis. Useful characteristics of diagnostic tests Accuracy and Precision Accuracy is the measure of a test result's accordance with results determined by a gold standard
Journal of Molecular Evolution 48: 337-340. Jamrt-Vierny, C., Boulay, J. & Briand, J-F. 1997. Contribution of various classes of defective mitochondrial DNA molecules to senescence in Podospora anserina. Current Genetics 31: 171-178. Jazwinski, S.M. 1996. Longevity assurance genes and mitochondrial DNA alterations: yeast and filamentous fungi. In: Handbook of the Biology of Aging (4th edition), p. 39. Academic Press, New York. Kamaletdinowa, F.I. & Vassilyev, A.E. 1982. Cytology of Discomycetes. Alma-Ata, 176 pp. Kempken, F. 1995. Horizontal transfer of a mitochondrial plasmid. Molecular & General Genetics 248: 89-94. Kempken, F. & Kuck, U. 1998. Transposons in filamentous fungi--facts and perspectives. Bioessays 20: 652-659. Kim, N.S., Park, N.I., Kim, S.H., Kim, S.T., Han, S.S. & Kang, K.Y. 2000. Isolation of TC/AG repeat microsatellite sequences for fingerprinting rice blast fungus and their possible horizontal transfer to plant species