Molekulaarbioloogia praksi kontrolltöö vastused
increased levels of serum catecholamines or urinary catecholamine metabolites as
described above.
The prognosis for patients with neuroblastoma is related to their age at diagnosis, clinical
stage of disease, and (in patients older than 1 year) regional lymph node
involvement. Other conventional prognostic variables include the site of the
primary tumor and tumor histology .
Cellular ClassificationOne clinicopathologic staging system involves evaluation of
tumor specimens for the amount of stromal development, the degree of neuroblastic
maturation, and the mitosis-karyorrhexis index of the neuroblastic cells. Favorable
and unfavorable prognoses are defined on the bases of these histologic parameters
and on patient age. The prognostic significance of this classification system, and of
related systems using similar criteria, has been confirmed in several studies.
annaabi.ee 
