Johne haigus - immunuloogia
Patogeen levib peamiselt alimentaarselt ja nakatab
looma peensoolt, harvem jämesoolt, põhjustades sooleseina paksenemist ja vähendades
toitainete imendumist. Seni ei ole leitud paratuberkuloosile ravi ja et vältida haiguse levikut,
haigestunud loom hukatakse.
Arsenault, R.J., Maattanen, P., Daigle, J., Potter, A., Griabel, P., Napper, S. From mouth to
macrophage: mechanisms of innate immune subversion by Mycobacterium avium subsp.
Paratuberculosis. Veterinary Research. 2014, 1-2
Bannatine, J.P., Bermudez, L.E. No Holes Barred: Invasion of the Intestinal Mucosa by
Mycobacterium avium subsp. Paratuberculosis. Infection and Immunity. 2013
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3811823/ 10.09.2017
Chaubey, K.K., Gupta R.D., Gupta, S., Singh, S.V., Bhatia, A.K., Jayaraman, S., Naveen, K.,
Goel, A., Rathore, A.S., Sahzad, Sohal, J.S., Stephen, B.J., Singh, M., Goyal, M., Dhama, K.,
Derakhsandeh, A. Trends and advances in the diagnosis and control of paratuberculosis in