"skoorimaatriksite" - 1 õppematerjal

Järjestuste võrdlemine, otsingud andmebaasidest (BLAST, FASTA, SW).

For nucleotide- nucleotide searches (i.e., "blastn") an exact match of the entire word is required before an extension is initiated, so that one normally regulates the sensitivity and speed of the search by increasing or decreasing the word-size. For other BLAST searches non-exact word matches are taken into account based upon the similarity between words. The amount of similarity can be varied so one normally uses just the word-sizes 2 and 3 for these searches. iv. Skoorimaatriksite varieerimine ­ kuidas mõjutab varieerimine. Skoori number sõltub kõige rohkem maatriksist, sõltuvalt ülesandest valitakse sobiv skoorimaatriks. Matrix A key element in evaluating the quality of a pairwise sequence alignment is the "substitution matrix", which assigns a score for aligning any possible pair of residues. The matrix used in a BLAST search can be changed depending on the type of sequences you are searching with (see the BLAST Frequently Asked Questions)