"noncancer" - 1 õppematerjal

Dioxins and furans in the atmosphere

Dioxins and furans are mainly distributed through the air. However, only a small percentage of exposure is from air. Eating contaminated food is the primary source of exposure.  Impact on Human Dioxins have been characterized as likely to be human carcinogens and are anticipated to increase the risk of cancer at background levels of exposure. At body burden levels 10 times or less above those attributed to average background exposure, adverse noncancer health effects have been observed both in animals and, to a more limited extent, in humans. In animals these effects include changes in hormone systems, alterations in fetal development, reduced reproductive capacity, and immunosuppression. Effects specifically observed in humans include changes in markers of early development and hormone levels. At much higher doses, dioxins can cause a serious skin disease in humans called chloracne.