depend on Similar Mechanisms We saw in Chapter 11 that synaptic changes underlying memory in at least some parts of the adult brain, notably the hippocampus, hinge on the behavior of a particular type of receptor for the neurotransmitter glutamate—the NMDA receptor. Ca2+ flooding into the postsynaptic cell through the channels opened by this receptor triggers lasting changes in the strengths of the synapses on that cell, affecting the presynaptic as well as the postsynaptic structures.
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